Not sure if it will help but here is the Fiddler RAW data from my test site when I am able to replicate the problem. Here are the steps that I take to replicate the behavior the users are experiencing
1) On my test site select a folder and click Open in Windows Explorer.
2) The windows explorer window opens successful
3) Close the windows explorer window
4) Attempt to reopen the same folder that was just closed via Open in Windows Explorer. The windows explorer window does not open.
POST
http://localhost/dnn7/Documents.aspx HTTP/1.1
Accept: */*
Content-Type: application/x-www-form-urlencoded
Referer:
http://localhost/dnn7/Documents.aspx Accept-Language: en-us
Accept-Encoding: gzip, deflate
User-Agent: Mozilla/5.0 (compatible; MSIE 9.0; Windows NT 6.1; WOW64; Trident/5.0)
Host: localhost
Content-Length: 79
Connection: Keep-Alive
Pragma: no-cache
Cookie: StayInEditMode=NO; .ASPXANONYMOUS=krROWhtRzgEkAAAAZDE3OTViOWItNTgzYS00ZjI3LWIxZjgtZWEyZjMyYTBiNjU00; language=en-US; ASP.NET_SessionId=pcc5avshzjvdq51hixm4zdhr; authentication=DNN; dmxdavcookie=B0AD; LastPageId=0:119; __RequestVerificationToken_L0ROTjc1=RJayrR1XLhvto8AesKFeBmq1LUZl05eMp_htht-6deGL1XeyyKCXYa8uaKrMwihmwBVa32qZU1nnF1qUbY-B5yfr90tyXXVFJT1wq1U3BtxL37OPjKHup4C1cpw1; .DOTNETNUKE=6A88C
Cart_dnn_ctr666_Dispatch_viewcollection_ContextMenuCallBack_Callback_Param=ent2